Fuzzy Controller for Automatic Drug Infusion in Cardiac Patients

Control of mean arterial blood pressure and cardiac output is highly desirable in certain operative procedures and in post cardiac operation. This paper emphasizes on a fuzzy controller to control these two variables within the present limits by administering three drugs dopamine, Sodium Nitro Prusside and Phenylephrine which perform the function of increasing heartbeat rate, decreases, increases blood pressure respectively. A fuzzy PD controller with 25 rules is designed to achieve this, which controls the drug delivery unit. This work makes use of few mathematical models whose response to these three drugs mimics the human cardiovascular system. This work can be extended by ASIC Fuzzy control system, which is capable of modeling the cardiovascular mechanism. Till now the usual procedure is that the clinical personal (anesthesio logist) will monitor the changes and will accordingly adjust the infusion rates. The main goals of general anesthesia are adequate hypnosis, analgesia and maintenance of vital functions. For some special kinds of operations neuromuscular block is essential. Furthermore the patient safety and cost reduction as a case of minimized drug consumption and shortened postoperative recovery phases are part of the main issues to motivate automation in anesthesia. Since the beginning of the eighties engineers and physician are working together in the field of the development of closed-loop systems for drug delivery. The work gives a short overview about the development of the automation in drug delivery systems over the last years without the claim of completeness and expressed the much more vision.